WASHINGTON -- U.S. first lady Jill Biden tested negative for COVID-19 after isolating for five days following a positive test, the White House said on Sunday.

"After isolating for five days and receiving negative results from two consecutive COVID-19 tests, the First Lady will depart South Carolina later today for Delaware," her spokesperson said in a statement.

The White House said on Tuesday that the first lady had tested positive and was experiencing mild symptoms. U.S. President Joe Biden himself also .

Jill Biden, who like her husband has been vaccinated twice and boosted twice with the Pfizer Inc COVID-19 vaccine, was prescribed a course of Paxlovid.

She was in South Carolina where the Bidens were on vacation.

When she tested positive on Tuesday, the White House said the president would wear a mask for 10 days when indoors and when in close proximity to others because he was considered a close contact of the first lady. This was in accordance with guidance from the Centers for Disease Control and Prevention (CDC).

The president returned to Washington on Tuesday to sign a landmark climate change and health-care bill, before continuing to his home in Wilmington, Delaware.