LOS ANGELES - Two beautiful doctors, an ornery agent, a cop, a shrink and a cheerleader will help hand out trophies at the Primetime Emmy Awards.

The actors behind these TV roles -- Katherine Heigl, Kate Walsh, Jeremy Piven, Jimmy Smits, Kelsey Grammer and Hayden Panettiere -- are among the presenters set to appear at the 59th Primetime Emmy Awards on Sept. 16, executive producer Ken Ehrlich announced Wednesday.

Other small-screen stars presenting prizes on TV's biggest night include Steve Carell, Kiefer Sutherland, Jon Stewart, Patricia Heaton, Kyle Chandler and the cast of "Entourage": Piven, Adrian Grenier, Kevin Connolly, Kevin Dillon and Jerry Ferrara.

The Primetime Emmy Awards, hosted by Ryan Seacrest, will be broadcast live from the Shrine Auditorium on CTV on Sept. 16 at 8pm ET.